1. Collectibles
1.1. All Collectible Locations (Blackboxes, Field Ops, Lairs)

2. Story-Related
2.1. Master Prototype (Complete the game on HARD difficulty)

3. Miscellaneous
3.1. The Floor is Lava – Traveled a half mile using Wall Run, Glide, Jump and Air Dash
3.2. Two for the Price of One – killed 2 Brawlers using a single Devastator
3.3. Arcade Action – Karate kicked a helicopter
3.4. Cannonball – 20 or more kills with a single Hammerfist dive attack
3.5. Icarus – Reached the highest point in the world
3.6. You’re the Bomb – 10 or more kills using a single Bio-Bomb
3.7. Strike You’re Out – Destroy a Strike Team in 15 seconds or less
3.8. So Above It All – Spend at least 25 consecutive seconds in the air
3.9. I Caught a Big One! – Mount a helicopter using Whipfist
3.10. All Together Now – 10 or more kills with a single Black Hole attack
3.11. Hijack Be Nimble – Stealth hijack 5 tanks or APCs.
3.12. Road Rage – Destroy 10 enemy vehicles using a single hijacked tank.

All Collectible Locations
There are a total of 82 collectibles in Prototype 2. Once they are in a radius of ~160 feet you will see them highlighted on the screen. If you go to your collectibles in-game map you can see little pulses that indicate missing collectibles. All collectibles are very easy to locate which makes videos needless. I decided to make a high resolution map instead of videos. It’s the faster and more comfortable way for you to gain all of the collectible related trophies / achievements.

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Master Prototype
Complete the game on HARD difficulty.
This can (and should) be done in New Game+! Simply complete all of the main plot missions on hard difficulty, without changing difficulty settings.
I recommend to do two playthroughs. Do the first one on easy and get all of the collectibles. Then you create a New Game+ on hard difficulty and mop up the remaining trophies. Hard difficulty itself is a piece of cake if you already have the upgrades from a previous playthrough. This playthrough will take you 5-6 hours only.
The hardest part is the final bossfight.

When fighting Alex Mercer on hard you won’t have a chance to refill your health during the rounds, but if you die you will restart the current round with full health. Alex is quite powerful if you try to fight him in direct combat (especially when he is using the whipfist). A good tactic is to equip the hammerfist, jump up as high as possible and smash back down to the ground by holding down the attack button. It takes some while, but is a safe and easy method to survive the whole fight without getting a scratch.

The Floor is Lava
Traveled a half mile using only Wall Run, Glide, Jump and Air Dash.
All you need for this are two tall buildings. Run up one of the buildings and jump to the other, but make sure to use Air Dash as well as the Glide ability. After doing this for 2 minutes the trophy / achievement should be yours.
The video shows you a very good location on the first island.

Two for the Price of One
Simultaneously killed 2 Brawlers using a single Devastator.
This can easily be done in the mission where you learn the Devastator ability. The mission is called ‘Orion Phase Two’ and takes place relatively early in the game, on the first island. Right after getting the ability you will need to consume some soldiers to power up your Devastator attack. A cutscene will begin to play and lots of Brawlers will come in (they look like orange glowing monsters with big claws). Damage two Brawlers until half of their health is gone and hold down Triangle + Circle (PS3) / Y + A (X360) when they are nearby.

You can also get this later in free roam or during other missions. The shown method is just the earliest and probably easiest opportunity to get it.

Arcade Action
Karate kicked a helicopter.
This can be done anywhere and at any time as long as a helicopter is chasing you. Jump as high as possible and hold down Square (PS3) / X (Xbox 360) while you are in the air. Make sure that you have your fists equipped and no other weapons!
The video shows you a very good spot in the mission called ‘Natural Selection’. Don’t worry if you miss it, you can get it any time in free roam.

Cannonball!
20 or more kills with a single Hammerfist dive attack.
This can easily be done in the mission where you learn the Hammerfist ability. The mission is called ‘A Nest of Vipers’ and takes place on the second island. Once you have the ability jump as high as possible and hold down Square (PS3) / X (Xbox 360) to launch a Hammerfist Dive attack. There are lots of infected people in the lair which should make this easy.
You can also get this later in free roam or during other missions. The shown method is just the earliest and probably easiest opportunity to get it.

Icarus
Reached the highest point in the world.
You can do this once you reach the third island (Red Zone). You will get there after progressing in the story. Airbridges allow you to travel from island to island.
Look out for the tallest building around the center of the Red Zone (Midtown district). Simply run all the way up the building until you reach highest point.

You’re the Bomb
10 or more kills using a single Bio-Bomb.
After getting the Bio-Bomb (during a mission on the second island) you can get this pretty much everywhere and at any time. It works best against infected people because they will run towards you in large hordes. You can find lots of them on the third island (Red Zone) and inside lairs. Grapple an enemy and press Square (PS3) / X (Xbox 360) to activate the Bio-Bomb. Throw the enemy into a group of at least 10 persons / enemies.

Strike, You’re Out.
Destroy a Strike Team in 15 seconds or less.
Strike teams are helicopters that will chase you after attacking enemy properties or soldiers. You will see a text warning saying “Strike Team inbound” if they are chasing you. On the screen the strike teams are marked with a red lightning in a circle shape.
It’s recommended to do this on the first island (Yellow Zone) because only one helicopter will be chasing you. On the second island there will be two helicopters and on the third one three helicopters. Get yourself a helicopter near an enemy base, make some damage to trigger the strike team and destroy it with your helicopter.
To enter helicopters you need to progress in the story until you reach the third island (red zone).
Alternatively, you can also buy the finisher upgrade that lets you take out helicopters immediately. Just jump on the helicopter and press triangle (PS3) / Y (Xbox 360) to destroy it.

So Above It All
Spend at least 25 consecutive seconds in the air (helicopters don’t count).
This will also earn you the Icarus trophy / achievement. Please check out theIcarus video guide on how to reach the highest point on the map.

Warning: You will have to max out Heller’s movement abilities first! You will need the Double Air Dash and the maxed out jump height. You can only do this after reaching the third island (Red Zone).
Once on top of the tallest building try to run up the pole in the middle and make a high jump by holding down X (PS3) / A (Xbox 360). Make sure that you didn’t waste any air dashes until this point. They are gonna save you a couple seconds on your way down. Once in the air keep tapping the ‘Glide-Button’ very quickly (R2 on PS3 / RT on Xbox 360). If you keep holding the button you will reach the ground too early. Once you begin to fall too quickly use your Air Dash. This will give you some extra height.

I Caught a Big One!
Mount a helicopter using Whipfist.
You will automatically learn the Whipfist ability during a main plot mission on the third island (Red Zone). Select the Whipfist in the weapon wheel and press Circle (PS3) / B (Xbox 360) while aiming on a helicopter. If you did it correctly, Heller should grapple the helicopter.

All Together Now
10 or more kills with a single Black Hole attack.
You will automatically learn the Black Hole ability during a main plot mission on the first island (Yellow Zone). You need to select the Tendrils in your weapon wheel and hold down the attack button. It does not matter if you kill 10 civilians, soldiers or infected. They all count as long as you kill 10 at once. You can find lots of infected inside lairs and on the streets of the third island (Red Zone).

Hijack Be Nimble
Stealth hijack 5 tanks or APCs.
Tanks and APCs are the armored vehicles you can drive. You will automatically learn the required ability during a main plot mission on the second island (Green Zone). You cannot enter any vehicles before this point of the game! Once you got the Amor Hijacking ability move to an enemy base and enter an enemy tank without causing an alert. You need to be in a military costume to avoid being detected. Stealth Hijack five different tanks or make them respawn by using airbridges. 

Road Rage
Destroy 10 Blackwatch tanks, APCs or helicopters using a single hijacked tank or APC.
You will automatically learn the Armor Hijacking ability during a main plot mission on the second island (Green Zone)
You should wait until you got some armor upgrades by consuming enemies (see Finally Full trophy). The best location to do this is on the third island (Red Zone) near the enemy base where the most northern airbridge is located. On the streets around this base are lots of moving tanks. Hijack one of the heavily armored ones, drive around to take out other ground units and destroy incoming strike teams and helicopters. The 10 kills have to be done with one single vehicle. If your vehicle gets destroyed, the counter will be reset.

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