1. Walkthrough
1.1. Mission 1: Ground Zeroes
1.2. Mission 2: Eliminate the Renegade Threat
1.3. Mission 3: Intel Operative Rescue
1.4. Mission 4: Classified Intel Acquisition
1.5. Mission 5: Destroy the Anti-Air Emplacements
1.6. Mission 6: Déjà-Vu

2. Collectibles
2.1. All XOF Unit Patches
2.2. All Cassette Tapes

3. Story-Related
3.1. Rescue (Ground Zeroes Story Mission)
3.2. Depth (Eliminate the Renegade Threat Side Op)
3.3. Pacifist (Intel Operative Rescue Side Op)
3.4. Infiltration (Classified Intel Acquisition Side Op)
3.5. Extraction (Destroy all Anti-Air Emplacements Side Op)
3.6. Reminiscence (Déjà-Vu Extra Op)

Hero
Clear all missions (including Side Ops and Extra Ops) with a S-rank
When going for S-Rank you should always turn off Reflex Mode in the Game Settings. This will give you extra points for every mission. S-Rank is completely based on your final point score at the end of a mission. Try to stay undetected, don’t kill any enemies (stunning them is okay), move quickly and try not to restart any checkpoints. It does not matter on which difficulty you are playing. Normal mode is recommended.

– Mission 1: Ground Zeroes –
The key to earning S-Rank in this mission is to rescue all prisoners in the area where you find Chico (the imprisoned boy). Rescuing everyone will give you 21,000 points. After finding Paz you should immediately call the helicopter. Put her in a truck and drive to the exfiltration point. It doesn’t really matter if you get detected at this point, as it will only deduct 300 points from your final score and in return you get bonus points for saving time. Sneaking out would take a lot longer and would be much harder as there are many enemy patrols.

– Mission 2: Eliminate the Renegade Threat –
The key to earning S-Rank in this mission is to kill both targets as quickly as possible without being detected. Don’t kill any other enemies.
This is one of the shortest missions. As you go up the hill you will see a bunch of enemies, stun all of them. There’s a parked truck up the road, where the helipads are located. On the back of the truck is a sniper rifle. That’s the key to get a quick S-rank.
Pick it up and climb the wooden watch tower near the area with the white tents. From here you can headshot both mission targets. Call the helicopter for a quick escape, take out both targets with a headshot and you’re done. Make sure you have stunned all of the guards around the watch tower or they will hear you and trigger an alarm!

– Mission 3: Intel Operative Rescue –
The key to earning S-Rank in this mission is not killing any enemies.
You can also get the “Pacifist” Trophy / Achievement during this mission. Only use the stun revolver. It doesn’t matter if enemies kill themselves or each other (e.g. by falling down a building or running over stunned enemies with a vehicle). This won’t influence your score. Destroying the tank at the end doesn’t count as a kill either. Just make sure you are not hitting any of the stunned enemies when shooting rockets at the tank.
When the helicopter spawns you have to take out its crew with the stun revolver. Don’t use the rocket launcher here.

– Mission 4: Classified Intel Acquisition –
The key to earning S-Rank in this mission is obtaining the mission objective without interrogating the undercover agent. This will save you a lot of time which is rewarded with lots of bonus points.
You can also get the Infiltration Trophy / Achievement during this mission.
Just wait on the back of the truck in the beginning. It will bring you to the admin building. Go up to the watch tower (by using the ladder) and grab the cassette tape. Once you have the tape you can leave the area. The least risky way to do so is to get back on the truck that brought you to the admin building. Just stay on the back of the truck for a couple of minutes until the driver returns. He will then bring you back to the starting point which will end the mission and earn you the Infiltration trophy / achievement.

– Mission 5: Eliminate the Anti-Air Emplacements –
Side Op: Destroy the Anti-Air Emplacements
The key to earning S-Rank in this mission is to shoot the explosive barrels next to the Anti-Air turrets and to destroy the incoming tank by placing C4 on the street. You should also rescue some prisoners in the 3 minutes you have left.
It is absolutely crucial that you stay undetected and do not kill anyone. Restarting checkpoints is okay. Enemies that die from exploding barrels do NOT count as kills. Blowing up the tank won’t count as a kill either. Just be sure to place C4 on the first Anti-Air turret. Then make your way up the road and shoot the explosive barrels next to the turrets on the helipad. Get in the truck and drive away. Now trigger the C4 from the first turret to make the tank spawn. Place C4 on the street to blow up the tank without being seen.
You don’t necessarily have to rescue any prisoners if you do this quickly enough, but they add good bonus points nonetheless. So on your way out, consider picking some of them up if you had to restart checkpoints or lost points elsewhere.

– Mission 6: Déjà-Vu –
Extra Op: Déjà-Vu
They key to earning S-Rank in this mission is to recreate 3-4 of the scenes and finish the mission as quickly as possible. There aren’t many enemies, so it’s fairly easy to sneak past them.

Insignia
Obtain all XOF unit patches
There are a total of 9 XOF Unit Patch Locations in Metal Gear Solid V: Ground Zeroes. Finding all XOF Unit Patches will earn you the “Insignia” Trophy / Achievement.
They will also unlock the “Déjà-Vu” Extra Op.

All of the XOF Patches are scattered across the “Ground Zeroes” mission. That’s the only main mission in the game and it’s available from the beginning on.
After picking up a collectible you need to reach the next checkpoint to save the progress. If you die before saving the game, you will have to collect it again.

The last XOF Unit Patch requires you to roll around on the ground. Hold X (PS3) / A (X360), then aim your weapon and hold down the left stick to start rolling. This will initiate a cutscene and the last patch will fall from the sky. Be sure you are somewhere outside when doing this. The other 8 unit patches can be picked up like normal collectibles, but they are hard to see. Pause the video and put a marker on your map to locate them easily.

The trophy / achievement will unlock after beating the story (which consists of only this one story mission). Shortly after the credits are over, you will see a screen with your rewards. That’s when it should unlock.

Information
Obtain all cassette tapes
There are a total of 17 Cassette Tape Locations in Metal Gear Solid V: Ground Zeroes. Finding all Cassette Tapes will earn you the “Information” Trophy / Achievement.

Only 12 Cassette Tapes need to be picked up manually. The other 5 will unlock automatically while you do this. Some can be picked up just like the XOF Unit Patches and others are a reward for rescuing certain prisoners, interrogating enemies or simply beating a mission with any rank. You also have to beat all missions (including the console specific extra op) on hard difficulty to unlock one of the tapes. Hard difficulty becomes available after beating a mission for the first time. To unlock the Extra Op you need to find all XOF Unit Patches. Please refer to the XOF Collectible Guide for more details.

Even though all Collectibles are on the same map, you will have to pick them up over the course of different missions. Each Tape only spawns within a certain mission. Be sure to collect them in the shown order! Some of the tapes disappear if you progress too far in a mission. If that happens you need to restart the mission from the beginning.
If you die you have to collect the cassette again! You have to reach the next checkpoint to save your progress. After that you can return to the title screen.

You can see how many Cassette Tapes you have found by going to “Play Records” in the title screen. Click on “Record Totals” and scroll all the way down. Each Tape has its own specific name. You can listen to them and see their names in the “Cassette Tapes” section of the title screen. Use this to see exactly which one you are missing.

Rescue
In the “Ground Zeroes” mission, rescue the prisoner to be executed and extract him via chopper
Mission: Ground Zeroes
This can be done in the very beginning of the mission. After opening the locked fence you will see an area with lots of white tents on the left side. In the north-western corner of this area, past the tents, is a wooden shack. Inside is a prisoner with orange clothing. Pick him up and call the extraction chopper. Put the man in the chopper by holding down Circle (PlayStation) / B (Xbox). The trophy / achievement will unlock right away.

Depth
Clear the “Eliminate the Renegade Threat” Side Op by extracting both targets
Side Op: Eliminate the Renegade Threat
To get this trophy / achievement you have to extract both enemies while they are still alive. You may knock them out of course, but do not kill them.
The first main target is located in the south, near the area with the white tents. He is a bald guy, patrolling along two other guards. You will spot him fairly easily because he is the only enemy without a hat. Be sure to get to him as quickly as possible after the mission starts. Now use the WU Silent Pistol to tranquilize him and the two other guards. Call the helicopter and extract him.
Now move north to where the helipads are located. In the big watch tower of the admin building is another soldier without a hat. Again guarded by two other enemies. Just go through the red door on the far left, take out all the guards and cameras and he will come down a ladder. You can kill his two bodyguards while they are going down the ladder. Knock him out and put him in the car that is parked in the same area. Now just drive out of the mission area while he is sitting inside and you are done.

Pacifist
Clear the “Intel Operative Rescue” Side Op without killing a single enemy
Mission: Intel Operative Rescue
Only use the stun revolver. It doesn’t matter if enemies kill themselves or each other (e.g. by falling down a building or running over stunned enemies with a vehicle). This won’t influence your score. Destroying the tank at the end doesn’t count as a kill either. Just make sure you are not hitting any of the stunned enemies when shooting rockets at the tank.
When the helicopter spawns you have to take out its crew with the stun revolver. Don’t use the rocket launcher here.

This can easily be combined with the S-Rank, as it is illustrated in the video below:

Infiltration
Clear the “Classified Intel Acquisition” Side Op while riding in the back of a truck
Mission: Classified Intel Acquisition
Just wait on the back of the truck in the beginning. It will bring you to the admin building. Go up to the watch tower (by using the ladder) and grab the cassette tape. Once you have the tape you can leave the area. The least risky way to do so is to get back on the truck that brought you to the admin building. Just stay on the back of the truck for a couple of minutes until the driver returns. He will then bring you back to the starting point which will end the mission and earn you the Infiltration trophy / achievement.

This can easily be combined with the S-Rank, as it is illustrated in the video below:

Extraction
In the “Destroy the Anti-Air Emplacements” Side Op, rescue and extract all prisoners via chopper
Side Op: Destroy the Anti-Air Emplacements
There are 4 prisoners you need to rescue. The first one is being held in the same cell where you found Paz during the Ground Zeroes main mission (in the basement of the admin building). Call the extraction helicopter to the beach at the east side of the map and safely carry the prisoner out.
The other 3 prisoners are all in the same spot. They are in the cells where you found Chico during the Ground Zeroes mission. That’s right next to the beach with the extraction point, so you don’t have to go far and there are very few enemies guarding this place. Just open their cells, call the helicopter again and extract everyone. All prisoners have to be alive when you extract them!

The trophy / achievement should pop right away after putting the fourth prisoner in the chopper. You don’t have to complete the mission.

Reminiscence
Recreate all scenes in the “Déjà-Vu” Extra Op
Extra Op: Déjà-Vu
This is a PlayStation exclusive mission. Your task is to interact with 7 objects in order to see flashbacks of the original Metal Gear Solid PS1 game. These objects are pretty close together, so it shouldn’t take long. Avoid being detected in the beginning and go to the helipad in the northern part of the map. If you kill the guards in front of the helipad or destroy the helicopter you won’t be able to trigger the flashback anymore.
Some of the other scenes can also become missable if you destroy their respective objects (jeep, tank, camera).

When pressing the options/start button you can scroll over to the mission objectives to see which scenes you have completed. You need to do all of them in one playthrough. The trophy will pop after finishing the mission. To end the mission you need to crawl through an air vent near the gate in the north.