Sanctuary is the 5th main story mission in Borderlands 3 (BL3). This walkthrough will guide you through all objectives of the Sanctuary Main Quest.
Sanctuary is unlocked when you complete main mission Taking Flight.
Planet: Pandora
Area: The Droughts
Quest Giver: Ellie upon turning in Taking Flight
Requirement: Complete Taking Flight
Recommended Level: Level 8
Reward: Money and a Rare shield “Overflowing Moxxi’s Embrace”
Mission Info: The Crimson Raiders are leaving Pandora, the stars your destination. More specifically, Promethea. Assuming the ship doesn’t fall apart before you leave orbit.
Objectives:
- Enter Ship
- Talk to Lilith
- Install astronav
- Check on Tannis; Check on Marcus; Check crew quarters
- Melee thermal control system; Check on Marcus; Check crew quarters
- Check on Tannis; Check on Marcus; Check crew quarters
- Check on Tannis; Check on Marcus; Release trapped crew
- Check on Tannis; Shoot fire suppressors 0/3; Release trapped crew
- Check on Tannis; Shoot fire suppressors 1/3; Release trapped crew
- Check on Tannis; Shoot fire suppressors 2/3; Release trapped crew
- Check on Tannis; Talk to Marcus; Release trapped crew
- Check on Tannis; Browse SDU case; Release trapped crew
- Talk to Ellie
- Open garage to space
- Go to supply closet
- Bang on Supply Door
- Find Moxxi’s nightclub
- Talk to Moxxi
- Follow Moxxi to the slots
- Use slot machine
- Take Eridium
- Buy something from Crazy Earl
- Pick up entropy accelerator
- Install entropy accelerator
- Return to the bridge
- Navigate to Promethea
- Talk to Lilith
Starting Location: Sanctuary
Enter Ship
From the start head back to the open area which you found Lilith. Once in the open area turn around and face the door you came through and you will see a set of stairs on either side of the door leading up. Follow the path forward up the balcony and head into the ship door following the waypoint.
Talk to Lilith
Once you get control of your character again head straight ahead to Lilith and speak to her.
Install astronav
Once Lilith is done speaking head to the control station right behind her and install the astronav.
Check on Tannis; Check on Marcus; Check crew quarters
Once gaining control of your character again you will need to go check on the people in the ship. Head down the hallway and make your way to the right until you see the infirmary.
Head inside and go towards the middle of the room and you will hear Tannis call out to you. She wants you to melee the thermal control system.
Melee thermal control system; Check on Marcus; Check crew quarters
On the left side of the room inside the infirmary you will see a desk and the waypoint will be on a computer on her desk, this is the thermal control system, head over and give the thing a big ole smack to reveal Tannis’ hiding place.
Check on Tannis; Check on Marcus; Check crew quarters
Leave the infirmary and continue heading forward down the long corridor and through the door ahead. Head to the back of the room towards the left and along the back wall you will see a ladder heading down saying ‘Deck B’, head down that ladder.
At the bottom head into the opening ahead of you and you will see the waypoint on a locked door, this is where the crew is. Approach the door to hear them plead for help.
Check on Tannis; Check on Marcus; Release trapped crew
The crew will request that you let them out by hitting the switch right next to the door:
Go up to the switch and pull the lever and it will open the door.
Check on Tannis; Check on Marcus; Check crew quarters
From that room head back into the foyer and head towards the waypoint. Head down the hall and you will be caught off guard by Marcus running out into the hallway ahead of you. He will ask you to shoot the fire suppressors in the area.
Check on Tannis; Shoot fire suppressors 0/3; Check crew quarters
Head into Marcus’ Munitions immediately to the right of Marcus and you will see the fire on the ground in front of his window. Right above the fire is a sprinkler system, shoot it to put out the first fire.
Check on Tannis; Shoot fire suppressors 1/3; Check crew quarters
Head through where the fire was into the room beyond and in the follow hallway you will see another fire. Above that fire is another sprinkler, shoot it to smolder fire number 2.
Check on Tannis; Shoot fire suppressors 2/3; Check crew quarters
Head straight through where the last fire was and head down the stairs ahead. Once you reach the bottom landing look immediately over the desk into the hallway to the right and you will see this fire and the suppression system on the right side of the room. Shoot this suppressor to put out the last fire.
Check on Tannis; Talk to Marcus; Check crew quarters
Once the final fire is put out head back upstairs and locate Marcus using the waypoint, he is standing in the path heading back out in front of his counter in his Munitions shop. Walk up to him and use the Talk option.
Check on Tannis; Browse SDU case; Check crew quarters
Upon completing his dialogue he will want you to go over to his counter to browse the SDU case which is where you will purchase upgrades for your ammo capacity for your guns. You DO NOT have to purchase anything from this SDU case but make sure you use it to see the upgrades.
Talk to Ellie
Head back to the foyer where the fast travel is which is where you set the crew free earlier and locate the stairs heading down to the Cargo Bay. It has Ellie’s name in a heart above the door:
Head down inside and speak with Ellie. She will open some shutters showing the cargo bay on fire.
Open Garage to Space
Immediately to the left of Ellie is a switch on the wall, pull it to open the doors of the garage pulling the cargo that is on fire out into space to be someone else’s problem.
Go to supply closet
Ellie will want you to head down into the actual Cargo Bay and into the supply closet but don’t worry, she is going to lead the way. Head down and into this lovely area:
Bang on Supply Door
Head to the back wall in the supply closet to visit Earl, the Eridium dealer. He will be irate and refuse to speak to you.
Find Moxxi’s nightclub
Follow the waypoint upstairs to find the nightclub Moxxi runs. Simply head in the door for an introduction to the madame:
Talk to Moxxi
Simply head inside straight ahead and talk to the Moxxi who is standing right in front of the bar.
Follow Moxxi to the slots
You literally don’t even have to move your character for this one. Moxxi will head over to the slot machines in her nightclub and she will want you to follow, they are simply immediately to your left.
Use slot machine
Walk up to the slot machine right next to Moxxi with the waypoint on it and Play Slots by click the action button on the machine.
Take Eridium
The slots will by default land on Eridium on all three slots rewarding you with a block of Eridium, use the action button to pick up the purple block of currency.
Buy something from Crazy Earl
Follow the waypoint back down to the Cargo Bay and head into the supply closet again and speak with Earl. You DO NOT need to purchase anything but instead just have to speak with him to see what he has for sale, he sells character skins and customizations.
Pick up entropy accelerator
Turn around and right on the floor in front of you will be the Entropy Accelerator, pick it up to proceed to the next step.
Install entropy accelerator
Head all the way back upstairs to the hallway with the Infirmary on it and the waypoint will be on a computer system in the hallway, interact with the computer fuse box with the waypoint.
Return to the bridge
Make your way back to the front of the ship where Lilith was previously and head back into the control room.
Navigate to Promethea
Use the computer in the middle of the room with the hologram of a sphere in the middle to select a destination. Your options are Pandora and Promethea, select Promethea.
Talk to Lilith
Upon regaining control of your vault hunter immediately turn to your right and Lilith will be standing there. Speak to her to find out what the plan of action is and get a shield as a reward.
This finishes Sanctuary main mission in Borderlands 3. Now the next quest Hostile Takeover becomes available.
Next Up: Hostile Takeover
For all other Mission Walkthroughs, check out our complete Borderlands 3 Walkthrough.
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